Presence of uterine pinopodes at the embryo endometrial interface during human implantation in vitro

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Presence of uterine pinopodes at the embryo-endometrial interface during human implantation in vitro.

In order to study changes occurring on the surfaces of human endometrial epithelial cells in the presence of an implanted blastocyst, we used scanning electron microscopy for investigation of five endometrial biopsies and three human implantation sites obtained in vitro. All specimens showed areas with endometrial pinopodes, separated by cells displaying microvilli or cilia at the apical surfac...

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Endometrial Exosomes/Microvesicles in the Uterine Microenvironment: A New Paradigm for Embryo-Endometrial Cross Talk at Implantation

Exosomes are nanoparticles (∼100 nm diameter) released from cells, which can transfer small RNAs and mRNA via the extracellular environment to cells at distant sites. We hypothesised that exosomes or the slightly larger microvesicles (100-300 nm) are released from the endometrial epithelium into the uterine cavity, and that these contain specific micro (mi)RNA that could be transferred to eithe...

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the morphological expression of endometrial pinopodes during implantation in mice after ovarian stimulation and progesterone injection

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Uterine Receptivity to Embryo Implantation

It is both flattering and humbling to be asked to address this topic, since quite a few people at this meeting could address it equally well or better. In fact, Koji wrote a review with almost exactly the same title 20 years ago (1). However, each of us would address the area somewhat differently. Over the years I have had the privilege of examining blastocysts and implantation sites of a large...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 1999

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/14.2.515